Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.62 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975959 | 0.85 | AGTR1 (0.75) | AGTR1AGTR2ABCB11EGFRERBB2 | |
| Azilsartan SCHEMBL284893 | 0.81 | AGTR2 (0.68) | AGTR1AGTR2ABCB11EGFRERBB2 | |
| Azilsartan SCHEMBL30604716 | 0.81 | AGTR2 (0.68) | AGTR1AGTR2ABCB11EGFRERBB2 | |
| SCHEMBL29257718 | 0.81 | PPARG (0.70) | AGTR1AGTR2ABCB11EGFRERBB2 | |
| SCHEMBL8563144 | 0.81 | AGTR1 (0.70) | AGTR1AGTR2ABCB11EGFRERBB2 | |
| SCHEMBL31364599 | 0.81 | PPARG (0.70) | AGTR1AGTR2ABCB11EGFRERBB2 | |
| SCHEMBL28927794 | 0.81 | AGTR1 (0.70) | AGTR1AGTR2ABCB11EGFRERBB2 | |
| SCHEMBL6849453 | 0.81 | AGTR1 (0.64) | AGTR1AGTR2ABCB11EGFRERBB2 | |
| Azilsartan SCHEMBL7017842 | 0.81 | AGTR2 (0.67) | AGTR1AGTR2ABCB11EGFRERBB2 | |
| Azilsartan SCHEMBL7017834 | 0.81 | AGTR2 (0.67) | AGTR1AGTR2ABCB11EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354766-A | 2-Ethoxy-1-((2'(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl) biphenyl-4-yl)methyl)benzimidazole-7-carboxylic acid; hypotensive agents; CNS activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |