Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 8/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2824959 | 0.86 | OXER1 (0.58) | OXER1HTR2AHTR6MAPK1SCN9A | |
| SCHEMBL30936110 | 0.83 | HTR6 (0.60) | OXER1HTR6 | |
| SCHEMBL5304010 | 0.83 | HTR2A (0.57) | OXER1HTR2AHTR6SCN9A | |
| SCHEMBL1068278 | 0.83 | OXER1 (0.68) | OXER1HTR2AHTR6BCHE | |
| SCHEMBL6425323 | 0.82 | HTR2A (0.53) | OXER1HTR2AHTR6SCN9A | |
| SCHEMBL27487257 | 0.82 | HTR2A (0.53) | OXER1HTR2AHTR6KMT2ASCN9A | |
| SCHEMBL7585800 | 0.82 | HTR2A (0.53) | OXER1HTR2AHTR6LMNASMN1; SMN2 | |
| SCHEMBL6426061 | 0.82 | HTR2A (0.53) | OXER1HTR2AHTR6LMNASMN1; SMN2 | |
| SCHEMBL27721427 | 0.81 | HTR2A (0.58) | OXER1HTR2AHTR6SCN9A | |
| SCHEMBL22411434 | 0.81 | OXER1 (0.72) | OXER1HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283343-A | Melatonin antagonists | WHITBY RESEARCH, INC. (US) | 1994-02-01 | — | — | US | disclosed |