Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.67 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | GALR3 | O60755 | 2/20 | 0.53 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302291 | 0.88 | PTAFR (0.55) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL8581273 | 0.87 | PTAFR (0.57) | PTAFRALDH1A1CYP3A4TSHRKDM4E | |
| SCHEMBL9303763 | 0.81 | PTAFR (0.55) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9303050 | 0.81 | PTAFR (0.59) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9302509 | 0.81 | PTAFR (0.83) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9302155 | 0.80 | PTAFR (0.58) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9302834 | 0.80 | PTAFR (1.00) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9303184 | 0.78 | CYP11B1 (0.51) | TNFRAB9AHDAC1HDAC6ALDH1A1 | |
| SCHEMBL9302266 | 0.78 | PTAFR (0.55) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9298869 | 0.77 | TNF (0.61) | PTAFRTNFGALR3NR2F2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |