Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.58 |
| ▸ | GALR3 | O60755 | 2/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303050 | 0.88 | PTAFR (0.59) | PTAFRGALR3NR2F2RAB9ATNF | |
| SCHEMBL9303746 | 0.80 | PTAFR (0.67) | PTAFRGALR3NR2F2RAB9ATNF | |
| SCHEMBL9302266 | 0.79 | PTAFR (0.55) | PTAFRGALR3NR2F2RAB9ATNF | |
| SCHEMBL9303064 | 0.77 | PTAFR (0.52) | PTAFRGALR3NR2F2RAB9ATNF | |
| SCHEMBL9302296 | 0.76 | PTAFR (0.52) | PTAFRGALR3NR2F2RAB9ATNF | |
| SCHEMBL9302291 | 0.75 | PTAFR (0.55) | PTAFRGALR3NR2F2RAB9ATNF | |
| SCHEMBL9302509 | 0.74 | PTAFR (0.83) | PTAFRGALR3NR2F2RAB9ATNF | |
| SCHEMBL9302834 | 0.73 | PTAFR (1.00) | PTAFRGALR3NR2F2RAB9ATNF | |
| SCHEMBL9303763 | 0.73 | PTAFR (0.55) | PTAFRGALR3NR2F2RAB9ATNF | |
| SCHEMBL8136726 | 0.73 | PTAFR (0.55) | PTAFRGALR3NR2F2RAB9ATNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |