Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.62 |
| ▸ | PLAU | P00749 | 8/20 | 0.61 |
| ▸ | F2 | P00734 | 7/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.61 |
| ▸ | PLG | P00747 | 6/20 | 0.61 |
| ▸ | PLAT | P00750 | 5/20 | 0.61 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.61 |
| ▸ | KLK1 | P06870 | 2/20 | 0.61 |
| ▸ | F10 | P00742 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.54 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304281 | 0.94 | PLAU (0.61) | ITGB3ITGA2BPLAUF2PRSS1 | |
| SCHEMBL9303041 | 0.92 | PLAU (0.61) | ITGB3ITGA2BPLAUF2PRSS1 | |
| SCHEMBL12348330 | 0.89 | MEN1 (0.67) | ITGB3ITGA2BPLAUF2PRSS1 | |
| SCHEMBL9305779 | 0.89 | PLAU (0.71) | PLAUF2PRSS1PLGPLAT | |
| SCHEMBL9303237 | 0.88 | PLAU (0.65) | PLAUF2PRSS1PLGPLAT | |
| SCHEMBL9303338 | 0.86 | F2 (0.67) | PLAUF2PRSS1PLGPLAT | |
| SCHEMBL24313036 | 0.84 | PARP1 (0.61) | ITGB3ITGA2BPLAUF2PRSS1 | |
| SCHEMBL13791589 | 0.83 | PLAU (0.71) | ITGB3ITGA2BPLAUF2PRSS1 | |
| SCHEMBL7503148 | 0.83 | KMT2A (0.55) | ITGB3ITGA2BPLAUF2PRSS1 | |
| SCHEMBL7503147 | 0.83 | KMT2A (0.55) | ITGB3ITGA2BPLAUF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |