Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.67 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.67 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.67 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.67 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.67 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.67 |
| ▸ | PLAU | P00749 | 10/20 | 0.59 |
| ▸ | PLAT | P00750 | 9/20 | 0.59 |
| ▸ | PLG | P00747 | 7/20 | 0.59 |
| ▸ | F10 | P00742 | 6/20 | 0.59 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | KLK1 | P06870 | 2/20 | 0.55 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891830 | 0.94 | KMT2A (0.64) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| Hydrochloric Acid SCHEMBL8994029 | 0.92 | F2 (0.71) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL10815124 | 0.88 | PRSS1 (0.69) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL15651643 | 0.87 | KMT2A (0.79) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL5004851 | 0.87 | NPC1 (0.68) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL4063687 | 0.87 | PTPN1 (0.66) | F2PRSS1PLAUPLATPLG | |
| SCHEMBL9304281 | 0.86 | PLAU (0.61) | F2PRSS1PLAUPLATPLG | |
| SCHEMBL9303344 | 0.86 | PLAU (0.74) | F2PRSS1PLAUPLATPLG | |
| SCHEMBL9303751 | 0.86 | ITGB3 (0.62) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL27465968 | 0.86 | PTPN1 (0.69) | F2PRSS1PRSS2PRSS3ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |