Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 16/20 | 0.71 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.71 |
| ▸ | PLG | P00747 | 8/20 | 0.71 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.71 |
| ▸ | F2 | P00734 | 7/20 | 0.71 |
| ▸ | PLAT | P00750 | 6/20 | 0.71 |
| ▸ | KLK1 | P06870 | 1/20 | 0.71 |
| ▸ | F10 | P00742 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303237 | 0.96 | PLAU (0.65) | PLAUPRSS1PLGKLKB1F2 | |
| SCHEMBL9303041 | 0.90 | PLAU (0.61) | PLAUPRSS1PLGKLKB1F2 | |
| SCHEMBL9304281 | 0.89 | PLAU (0.61) | PLAUPRSS1PLGKLKB1F2 | |
| SCHEMBL9303751 | 0.89 | ITGB3 (0.62) | PLAUPRSS1PLGKLKB1F2 | |
| SCHEMBL9303344 | 0.89 | PLAU (0.74) | PLAUPRSS1PLGKLKB1F2 | |
| SCHEMBL7335930 | 0.86 | PLAU (0.78) | PLAUPRSS1PLGKLKB1F2 | |
| SCHEMBL5566603 | 0.86 | PLAU (0.78) | PLAUPRSS1PLGKLKB1F2 | |
| SCHEMBL9305440 | 0.85 | PLAU (0.68) | PLAUPRSS1PLGKLKB1F2 | |
| SCHEMBL23751130 | 0.84 | PLAU (0.86) | PLAUPRSS1PLGKLKB1F2 | |
| SCHEMBL9303249 | 0.84 | PLAU (0.60) | PLAUPRSS1PLGKLKB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |