Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303288 | 0.81 | GABRR1 (0.34) | ALDH1A1 | |
| SCHEMBL2123154 | 0.80 | TDP1 (0.50) | ALDH1A1TDP1CA2FFAR1 | |
| SCHEMBL15981255 | 0.73 | — | — | |
| SCHEMBL1478279 | 0.73 | TDP1 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL31270908 | 0.72 | ALOX15 (0.44) | ALDH1A1TDP1 | |
| SCHEMBL812164 | 0.71 | — | — | |
| SCHEMBL5804866 | 0.71 | TSHR (0.30) | — | |
| SCHEMBL8137496 | 0.71 | TDP1 (0.42) | ALDH1A1TDP1CA2FFAR1 | |
| SCHEMBL3685563 | 0.69 | — | — | |
| SCHEMBL1572411 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342767-A | Transferring a hydride ion from an R-configured alcohol to the pro-R face of nicotinamide adenine dinucleotide phosphate | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-08-30 | — | — | US | disclosed |
| US-5225339-A | NADPH <--> NADP | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-07-06 | — | — | US | disclosed |