Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11966705 | 0.82 | FYN (0.36) | ALDH1A1MAPTHIF1AHSD17B10 | |
| SCHEMBL3195465 | 0.82 | NPC1 (0.30) | MAPT | |
| SCHEMBL2970214 | 0.75 | — | — | |
| SCHEMBL26291212 | 0.75 | CYP3A4 (0.41) | ALDH1A1CYP1A2CYP3A4ALOX15MAPK1 | |
| SCHEMBL9442055 | 0.74 | CA1 (0.31) | — | |
| SCHEMBL19130837 | 0.72 | LMNA (0.40) | CYP1A2CYP3A4CYP2D6PKMHPGD | |
| SCHEMBL6913081 | 0.72 | NOS3 (0.32) | — | |
| SCHEMBL1618923 | 0.71 | CA1 (0.30) | — | |
| SCHEMBL30724646 | 0.71 | CYP1A2 (0.32) | CYP1A2 | |
| SCHEMBL2971647 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292736-A | Morpholinoalkylindenes as antiglaucoma agents | STERLING WINTHROP INC. (US) | 1994-03-08 | — | — | US | disclosed |