Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 4/20 | 0.57 |
| ▸ | MMP8 | P22894 | 2/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.57 |
| ▸ | GGH | Q92820 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282302 | 0.92 | GAA (0.59) | MMP9MMP8MMP13ADAMTS4GGH | |
| SCHEMBL9304277 | 0.80 | MAPT (0.48) | GGHGAAMMP2FOLH1LMNA | |
| SCHEMBL9304269 | 0.80 | MAPT (0.48) | GGHGAAMMP2FOLH1LMNA | |
| SCHEMBL2252322 | 0.75 | CA2 (0.66) | MMP9MMP8MMP13ADAMTS4GAA | |
| SCHEMBL8237305 | 0.75 | CA2 (0.66) | MMP9MMP8MMP13ADAMTS4GAA | |
| SCHEMBL60371 | 0.75 | GAA (0.62) | MMP9MMP8MMP13ADAMTS4GGH | |
| SCHEMBL60370 | 0.75 | GAA (0.62) | MMP9MMP8MMP13ADAMTS4GGH | |
| SCHEMBL8418984 | 0.75 | FOLH1 (0.42) | GGHFOLH1 | |
| SCHEMBL2246065 | 0.74 | PTPN1 (0.60) | ADAMTS4GAAMMP12FOLH1SMN1; SMN2 | |
| SCHEMBL4623122 | 0.74 | PTPN1 (0.60) | ADAMTS4GAAMMP12FOLH1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312565-A | Nonlinear optical materials | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| EP-0546113-A1 | NONLINEAR OPTICAL MATERIALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992003417-A2 | NONLINEAR OPTICAL MATERIALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-05 | — | — | WO | disclosed |