SCHEMBL60371

SCHEMBL60371

O=C(O)CC[C@H](Nc1ccccc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.62
NAALAD2 Q9Y3Q0 6/20 0.55
GGH Q92820 1/20 0.55
MMP9 P14780 1/20 0.53
MMP8 P22894 1/20 0.53
MMP13 P45452 1/20 0.53
ADAMTS4 O75173 1/20 0.53
FOLH1 Q04609 6/20 0.52
RIMKLA Q8IXN7 1/20 0.50
KMT2A Q03164 1/20 0.48
CPA3 P15088 1/20 0.47
KEAP1 Q14145 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60370 1.00 GAA (0.62) GAANAALAD2GGHMMP9MMP8
SCHEMBL16402636 0.89 GAA (0.51) GAANAALAD2GGHMMP9MMP8
SCHEMBL3448327 0.86 KMT2A (0.64) GAANAALAD2GGHMMP9MMP8
SCHEMBL30818291 0.86 GAA (0.48) GAANAALAD2GGHMMP9MMP8
SCHEMBL3448329 0.86 KMT2A (0.64) GAANAALAD2GGHMMP9MMP8
SCHEMBL4821017 0.86 GAA (0.51) GAANAALAD2GGHMMP9MMP8
Hydrochloric Acid SCHEMBL23834278 0.84 KMT2A (0.62) GAANAALAD2GGHMMP9MMP8
SCHEMBL5497952 0.84 FOLH1 (0.59) GAAGGHFOLH1
SCHEMBL11835127 0.84 GGH (0.48) GAANAALAD2GGHMMP9MMP8
SCHEMBL28535426 0.84 GGH (0.48) GAANAALAD2GGHMMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129092-B2 Resist pattern thickening material and process for forming resist pattern, and semiconductor device and method for manufacturing the same FUJITSU LIMITED (JP) 2012-03-06 US claimed
CN-1975571-B Resist pattern thickening material and process for forming resist pattern, and semiconductor device and method for manufacturing the same FUJITSU LTD 2011-04-06 CN claimed
US-20240025946-A1 Cyclic Tetrapeptides and Metal Complexes Thereof Universität Zürich (CH) 2024-01-25 US disclosed
US-11124520-B2 Cyclopenta[d]pyrimidines and substituted cyclopenta[d]pyrimidines as antitubulin and microtubule targeting agents, monocyclic pyrimidines as tubulin inhibitors, and pyrrolopyrimidines as targeted antifolates and tubulin and multiple receptor tyrosine kinase inhibitor and antitumor agents DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) 2021-09-21 US disclosed
US-20200181152-A1 Cyclopenta[d]pyrimidines And Substituted Cyclopenta[d]pyrimidines As Antitubulin and Microtubule Targeting Agents, Monocyclic Pyrimidines As Tubulin Inhibitors, And Pyrrolopyrimidines As Targeted Antifolates And Tubulin and Multiple Receptor Tyrosine Kinase Inhibition And Antitumor Agents DUQUESNE UNIVERSITY OF THE HOLY SPIRIT 2020-06-11 US disclosed
US-10538527-B2 Cyclopenta[d]pyrimidines and substituted cyclopenta[d]pyrimidines as antitubulin and microtubule targeting agents, monocyclic pyrimidines as tubulin inhibitors, and pyrrolopyrimidines as targeted antifolates and tubulin and multiple receptor tyrosine kinase inhibition and antitumor agents DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) 2020-01-21 US disclosed
US-20190241571-A1 Cyclopenta[d]pyrimidines And Substituted Cyclopenta[d]pyrimidines As Antitubulin and Microtubule Targeting Agents, Monocyclic Pyrimidines As Tubulin Inhibitors, And Pyrrolopyrimidines As Targeted Antifolates And Tubulin and Multiple Receptor Tyrosine Kinase Inhibition And Antitumor Agents DUQUESNE UNIVERSITY OF THE HOLY SPIRIT 2019-08-08 US disclosed
US-10239880-B2 Cyclopenta[d]pyrimidines and substituted cyclopenta[d]pyrimidines as antitubulin and microtubule targeting agents, monocyclic pyrimidines as tubulin inhibitors, and pyrrolopyrimidines as targeted antifolates and tubulin and multiple receptor tyrosine kinase inhibition and antitumor agents DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) 2019-03-26 US disclosed
US-20160304525-A1 Cyclopenta[d]pyrimidines And Substituted Cyclopenta[d]pyrimidines As Antitubulin and Microtubule Targeting Agents, Monocyclic Pyrimidines As Tubulin Inhibitors, And Pyrrolopyrimidines As Targeted Antifolates And Tubulin and Multiple Receptor Tyrosine Kinase Inhibition And Antitumor Agents DUQUESNE UNIVERSITY OF THE HOLY SPIRIT 2016-10-20 US disclosed
WO-2016168637-A2 CYCLOPENTA[D]PYRIMIDINES AND SUBSTITUTED CYCLOPENTA[D]PYRIMIDINES AS ANTITUBULIN AND MICROTUBULE TARGETING AGENTS, MONOCYCLIC PYRIMIDINES AS TUBULIN INHIBITORS, AND PYRROLOPYRIMIDINES AS TARGETED ANTIFOLATES AND TUBULIN AND MULTIPLE RECEPTOR TYROSINE KINASE INHIBITION AND ANTITUMOR AGENTS DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) 2016-10-20 WO disclosed
US-8906598-B2 Pattern forming method, method for manufacturing semiconductor device, and material for forming coating layer of resist pattern FUJITSU LIMITED (JP) 2014-12-09 US disclosed
EP-1793274-A2 Resist pattern thickening material and process for forming resist pattern, and semiconductor device and method for manufacturing the same FUJITSU LIMITED (JP) 2007-06-06 EP disclosed
CN-1975571-A Resist pattern thickening material and process for forming resist pattern, and semiconductor device and method for manufacturing the same FUJITSU LTD (JP) 2007-06-06 CN disclosed
US-20070123623-A1 Resist pattern thickening material and process for forming resist pattern, and semiconductor device and method for manufacturing the same FUJITSU LIMITED (JP) 2007-05-31 US disclosed
WO-2006102594-A1 NUCLEOSIDE PRODRUGS FOR TREATING VIRAL INFECTIONS GENELABS TECHNOLOGIES, INC. (US) 2006-09-28 WO disclosed
EP-1656387-A2 NUCLEOBASE PHOSPHONATE ANALOGS FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. (US) 2006-05-17 EP disclosed
WO-2005012324-A2 NUCLEOBASE PHOSPHONATE ANALOGS FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. (US) 2005-02-10 WO disclosed
CN-1468095-A Colloidal suspension of submicronic particles for carrying hydrophilic active principles (insulin) and method for preparing same ÷ 2004-01-14 CN disclosed
EP-1228083-A2 THERAPEUTIC TREATMENT OF ANDROGEN RECEPTOR DRIVEN CONDITIONS Hollis-Eden Pharmaceuticals Inc. (US) 2002-08-07 EP disclosed
WO-2001023405-A2 THERAPEUTIC TREATMENT OF ANDROGEN RECEPTOR DRIVEN CONDITIONS HOLLIS-EDEN PHARMACEUTICALS, INC. (US) 2001-04-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304525-A1 Cyclopenta[d]pyrimidines And Substituted Cyclopenta[d]pyrimidines As Antitubulin and Microtubule Targeting Agents, Monocyclic Pyrimidines As Tubulin Inhibitors, And Pyrrolopyrimidines As Targeted Antifolates And Tubulin and Multiple Receptor Tyrosine Kinase Inhibition And Antitumor Agents FOLR1, TUBB1, TUBA1C GAA 3877/4885NAALAD2 3670/4885GGH 1961/4885
US-20200181152-A1 Cyclopenta[d]pyrimidines And Substituted Cyclopenta[d]pyrimidines As Antitubulin and Microtubule Targeting Agents, Monocyclic Pyrimidines As Tubulin Inhibitors, And Pyrrolopyrimidines As Targeted Antifolates And Tubulin and Multiple Receptor Tyrosine Kinase Inhibition And Antitumor Agents FOLR1, DHFR, TUBB3 GAA 3538/4885NAALAD2 3067/4885GGH 1852/4885
US-20190241571-A1 Cyclopenta[d]pyrimidines And Substituted Cyclopenta[d]pyrimidines As Antitubulin and Microtubule Targeting Agents, Monocyclic Pyrimidines As Tubulin Inhibitors, And Pyrrolopyrimidines As Targeted Antifolates And Tubulin and Multiple Receptor Tyrosine Kinase Inhibition And Antitumor Agents TUBB, TUBB1, TUBA1C GAA 4099/4885NAALAD2 2929/4885GGH 2606/4885
US-20240025946-A1 Cyclic Tetrapeptides and Metal Complexes Thereof VIP, PTMS, PEPD GAA 358/4885NAALAD2 151/4885GGH 106/4885
US-10239880-B2 Cyclopenta[d]pyrimidines and substituted cyclopenta[d]pyrimidines as antitubulin and microtubule targeting agents, monocyclic pyrimidines as tubulin inhibitors, and pyrrolopyrimidines as targeted antifolates and tubulin and multiple receptor tyrosine kinase inhibition and antitumor agents FOLR1, TUBB1, TUBA1C GAA 3877/4885NAALAD2 3670/4885GGH 1961/4885
US-11124520-B2 Cyclopenta[d]pyrimidines and substituted cyclopenta[d]pyrimidines as antitubulin and microtubule targeting agents, monocyclic pyrimidines as tubulin inhibitors, and pyrrolopyrimidines as targeted antifolates and tubulin and multiple receptor tyrosine kinase inhibitor and antitumor agents FOLR1, DHFR, TUBB3 GAA 3550/4885NAALAD2 3058/4885GGH 1860/4885
US-10538527-B2 Cyclopenta[d]pyrimidines and substituted cyclopenta[d]pyrimidines as antitubulin and microtubule targeting agents, monocyclic pyrimidines as tubulin inhibitors, and pyrrolopyrimidines as targeted antifolates and tubulin and multiple receptor tyrosine kinase inhibition and antitumor agents TUBB, TUBB1, TUBA1C GAA 4099/4885NAALAD2 2929/4885GGH 2606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.