Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9245692 | 1.00 | TSHR (0.42) | TSHRALDH1A1P2RX7SOAT2SOAT1 | |
| SCHEMBL1610408 | 1.00 | TSHR (0.42) | TSHRALDH1A1P2RX7SOAT2SOAT1 | |
| SCHEMBL1610543 | 1.00 | TSHR (0.42) | TSHRALDH1A1P2RX7SOAT2SOAT1 | |
| SCHEMBL1610236 | 0.98 | ALDH1A1 (0.43) | TSHRALDH1A1P2RX7SOAT2SOAT1 | |
| SCHEMBL1611320 | 0.92 | TSHR (0.45) | TSHRALDH1A1P2RX7TP53CYP2D6 | |
| SCHEMBL1610200 | 0.85 | CNR1 (0.37) | TSHRP2RX7FAAHCYP2D6CNR1 | |
| SCHEMBL1612511 | 0.85 | CNR1 (0.37) | TSHRP2RX7FAAHCYP2D6CNR1 | |
| SCHEMBL1610013 | 0.84 | TSHR (0.48) | TSHRALDH1A1TP53CYP2D6HTT | |
| SCHEMBL1611455 | 0.83 | TLR8 (0.36) | TSHRALDH1A1P2RX7FAAHCNR1 | |
| SCHEMBL3602229 | 0.79 | CA12 (0.44) | ALDH1A1CYSLTR2CYSLTR1EPHX2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354729-A | Controlling weeds at low dosage; nonphytotoxic | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0579469-A2 | N-acyldihydroquinoline derivatives as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-01-19 | — | — | EP | disclosed |