Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1611320 | 0.87 | TSHR (0.45) | TSHRALDH1A1ACHERAB9AKDM4E | |
| SCHEMBL1610236 | 0.85 | ALDH1A1 (0.43) | TSHRALDH1A1ACHERAB9AKDM4E | |
| SCHEMBL5012483 | 0.84 | TSHR (0.38) | TSHRALDH1A1ACHERAB9AKDM4E | |
| SCHEMBL1610408 | 0.84 | TSHR (0.42) | TSHRALDH1A1CYP1A2CYP2C19TP53 | |
| SCHEMBL9303850 | 0.84 | TSHR (0.42) | TSHRALDH1A1CYP1A2CYP2C19TP53 | |
| SCHEMBL1610543 | 0.84 | TSHR (0.42) | TSHRALDH1A1CYP1A2CYP2C19TP53 | |
| SCHEMBL9245692 | 0.84 | TSHR (0.42) | TSHRALDH1A1CYP1A2CYP2C19TP53 | |
| SCHEMBL369840 | 0.83 | TSHR (0.54) | TSHRALDH1A1ACHERAB9AKDM4E | |
| SCHEMBL1611497 | 0.83 | TRPA1 (0.37) | TSHRALDH1A1ACHECYP1A2CYP2D6 | |
| SCHEMBL5008803 | 0.82 | TSHR (0.36) | TSHRALDH1A1ACHERAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543919-B1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS IN THE MANUFACTURE OF A MEDICAMENT FOR TREATMENT OF CNS DISEASES | SEARLE & CO (US) | 1996-04-10 | — | — | EP | claimed |
| EP-0543919-A1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS FOR TREATMENT OF CNS DISEASES. | SEARLE & CO (US) | 1993-06-02 | — | — | EP | claimed |
| WO-1992003131-A1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS FOR TREATMENT OF CNS DISEASES | G.D. SEARLE & CO. (US) | 1992-03-05 | — | — | WO | claimed |
| EP-0234944-A1 | Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-02 | — | — | EP | claimed |
| CN-113831487-A | Aromatic carboxylate intermediate, preparation method thereof and application thereof in ester type polycarboxylate superplasticizer | 江苏苏博特新材料股份有限公司 | 2021-12-24 | — | — | CN | disclosed |
| WO-2021107870-A1 | ANTIMICROBIAL AGENT, COATING FORMULATION, COMPOSITE SURFACE COATING AND METHODS OF PREPARING THE SAME | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2021-06-03 | — | — | WO | disclosed |
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2019-10-22 | — | — | US | disclosed |
| US-9802902-B2 | Antifungal compound | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-10-31 | — | — | US | disclosed |
| US-20170037013-A1 | ANTIFUNGAL COMPOUND | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-02-09 | — | — | US | disclosed |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2016-11-24 | — | — | US | disclosed |
| US-9493424-B2 | Antifungal compound | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-11-15 | — | — | US | disclosed |
| US-20150203454-A1 | ANTIFUNGAL COMPOUND | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-07-23 | — | — | US | disclosed |
| EP-0401166-A2 | Nitrogen-containing titanocenes and their use | CIBA-GEIGY AG (CH) | 1990-12-05 | — | — | EP | disclosed |
| US-4906764-A | Process for producing phosphinylamino acid derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0338702-A1 | Nonlinear optical materials | NIPPON OIL CO. LTD. (JP) | 1989-10-25 | — | — | EP | disclosed |
| US-4857427-A | Recording medium | NIPPON OIL COMPANY, LIMITED (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0318893-A2 | Titanocenes, their use and N-substituted fluoroanilines | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |
| EP-0292918-A1 | Process for producing phosphinylamino acid derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |
| EP-0232113-A2 | Recording medium including a glutamate copolymer | NIPPON OIL CO. LTD. (JP) | 1987-08-12 | — | — | EP | disclosed |
| EP-0226429-A2 | Optical filter comprising a glutamate copolymer and a method of making an optical filter comprising glutamate copolymer | NIPPON OIL CO. LTD. (JP) | 1987-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | CBR1, HAO2, CBR3 | TSHR 648/4885ALDH1A1 151/4885ACHE 4671/4885 |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | CBR1, HAO2, CBR3 | TSHR 648/4885ALDH1A1 151/4885ACHE 4671/4885 |
| US-20150203454-A1 | ANTIFUNGAL COMPOUND | ERG28, DPM1, BAK1 | TSHR 4379/4885ALDH1A1 3011/4885ACHE 4790/4885 |
| US-20170037013-A1 | ANTIFUNGAL COMPOUND | ERG28, DPM1, BAK1 | TSHR 4379/4885ALDH1A1 3011/4885ACHE 4790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.