Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304078 | 1.00 | DPP7 (0.50) | DPP7DPP8DPP9GNAI3GNAO1 | |
| SCHEMBL9637291 | 0.95 | DPP8 (0.46) | DPP7DPP8DPP9GNAI3GNAO1 | |
| SCHEMBL9637284 | 0.95 | DPP8 (0.46) | DPP7DPP8DPP9GNAI3GNAO1 | |
| SCHEMBL6434681 | 0.87 | DPP8 (0.50) | DPP7DPP8DPP9GNAI3GNAO1 | |
| SCHEMBL3060526 | 0.86 | DPP8 (0.42) | DPP7DPP8DPP9GNAI3GNAO1 | |
| SCHEMBL6438575 | 0.85 | DPP8 (0.49) | DPP7DPP8DPP9GNAI3GNAO1 | |
| SCHEMBL9636709 | 0.81 | MMP2 (0.47) | — | |
| SCHEMBL9637159 | 0.81 | MMP2 (0.47) | — | |
| SCHEMBL9637155 | 0.81 | MMP2 (0.47) | — | |
| SCHEMBL9636716 | 0.81 | MMP2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268678-B1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-29 | — | — | EP | claimed |
| US-4892939-A | ANTITUMOR, ANTIVIRAL AND IMMUNOSUPRESSIVE AGENTS | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-09 | — | — | US | claimed |
| EP-0268678-A1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-06-01 | — | — | EP | claimed |
| US-5356781-A | Zymogen activation peptides (ZAP) in the diagnosis of disease | BIOSCIENCE INTERNATIONAL, INC. (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0258995-B1 | Diagnosis, severity prediction, and monitoring of disease by immunoassay of free activation peptides of pancreatic zymogens | BIOSCIENCE INT INC (US) | 1994-04-13 | — | — | EP | disclosed |
| US-4948723-A | ASSAYING BODY FLUIDS FOR ACTIVATION PEPTIDES OF PANCREATIV ZYMOGENS CLEAVED BY PROTEOLYSIS | BIOSCIENCE INTERNATIONAL, INC. (US) | 1990-08-14 | — | — | US | disclosed |
| EP-0258995-A1 | Diagnosis, severity prediction, and monitoring of disease by immunoassay of free activation peptides of pancreatic zymogens | BIOSCIENCE INTERNATIONAL, INC. (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1988001059-A1 | DIAGNOSIS OF PANCREATIC DISEASE | BIOSCIENCE INTERNATIONAL INC. (US) | 1988-02-11 | — | — | WO | disclosed |