Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19928526 | 0.84 | MAPT (0.36) | BTN3A1MAPTBACE1CYP2C19SLC1A3 | |
| SCHEMBL17159642 | 0.83 | MAPT (0.36) | MAPTCYP2C19SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL17159638 | 0.83 | MAPT (0.36) | MAPTCYP2C19SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL15652722 | 0.83 | MAPT (0.36) | MAPTCYP2C19SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14747384 | 0.83 | MAPT (0.35) | BTN3A1MAPTBACE1 | |
| SCHEMBL15892778 | 0.81 | MAPT (0.37) | BTN3A1MAPTBACE1CYP2C19SLC1A3 | |
| SCHEMBL9304310 | 0.81 | MAPT (0.41) | BTN3A1MAPTBACE1CYP2C19SLC1A3 | |
| SCHEMBL9304303 | 0.81 | MAPT (0.41) | BTN3A1MAPTBACE1CYP2C19SLC1A3 | |
| SCHEMBL19928560 | 0.81 | CA2 (0.34) | BTN3A1MAPT | |
| SCHEMBL15892776 | 0.80 | MAPT (0.33) | BTN3A1MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332807-A | Process of producing 8A- and 9A-azalide antibiotics | MERCK & CO., INC. (US) | 1994-07-26 | — | — | US | disclosed |
| WO-1994015617-A1 | 8A-AZA AND 9A-AZA MACROLIDE ANTIBIOTICS, AND A PROCESS FOR PRODUCING SAME AND METHODS OF USE | MERCK & CO., INC. (US) | 1994-07-21 | — | — | WO | disclosed |