Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | IDO1 | P14902 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303096 | 0.85 | HDAC1 (0.61) | HDAC1HDAC6IDO1LMNAMEN1 | |
| SCHEMBL9304188 | 0.84 | HDAC1 (0.59) | HDAC1HDAC6IDO1LMNAMEN1 | |
| SCHEMBL12850040 | 0.80 | HDAC6 (1.00) | HDAC1HDAC6IDO1LMNACYP11B1 | |
| SCHEMBL4511949 | 0.79 | HDAC1 (0.70) | HDAC1HDAC6IDO1LMNAMEN1 | |
| SCHEMBL3539977 | 0.78 | HDAC1 (0.75) | HDAC1HDAC6IDO1 | |
| SCHEMBL28326064 | 0.77 | CYP11B1 (0.73) | HDAC1HDAC6IDO1LMNAMEN1 | |
| SCHEMBL4506350 | 0.77 | HDAC1 (0.64) | HDAC1HDAC6IDO1LMNAMEN1 | |
| Potassium Ion SCHEMBL9302514 | 0.76 | HDAC1 (0.70) | HDAC1HDAC6IDO1LMNACYP11B1 | |
| SCHEMBL4507749 | 0.76 | HDAC1 (0.66) | HDAC1HDAC6IDO1LMNAMAPT | |
| SCHEMBL1750364 | 0.76 | HDAC1 (0.73) | HDAC1HDAC6IDO1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |