Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19914324 | 0.81 | AGPAT2 (0.37) | PIK3CGSLC16A3ELANERAB9AMEN1 | |
| SCHEMBL19914415 | 0.77 | SMN1; SMN2 (0.40) | PIK3CGSLC16A3RAB9AMEN1NPC1 | |
| SCHEMBL2541637 | 0.76 | KDM4E (0.59) | PIK3CGELANERAB9AMEN1NPC1 | |
| SCHEMBL895172 | 0.75 | PIK3CG (0.66) | PIK3CGPSMB5RAB9ANPC1CASP3 | |
| SCHEMBL24999938 | 0.75 | TERT (0.42) | APPTERTEGFRAPAF1SLC16A3 | |
| SCHEMBL62512 | 0.75 | MAPT (0.56) | APPTERTEGFRAPAF1SLC16A3 | |
| SCHEMBL19899588 | 0.73 | POLB (0.45) | APPEGFRPIK3CGAPAF1PSMB5 | |
| SCHEMBL11170826 | 0.72 | PIK3CG (0.43) | PIK3CGPSMB5RAB9AMEN1NPC1 | |
| SCHEMBL15157800 | 0.72 | NPC1 (0.58) | PIK3CGPSMB5RAB9AMEN1NPC1 | |
| SCHEMBL20552113 | 0.72 | PIK3CG (0.43) | PIK3CGPSMB5MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |