Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304582 | 1.00 | CA12 (0.50) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL9305195 | 1.00 | CA12 (0.50) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL14611984 | 0.91 | CHRM1 (0.45) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL14611981 | 0.91 | CHRM1 (0.45) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL14611982 | 0.91 | CHRM1 (0.45) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL14611983 | 0.91 | CHRM1 (0.45) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL12396390 | 0.86 | ALDH1A1 (0.48) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL12396392 | 0.83 | TRPV1 (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL30619593 | 0.82 | ALDH1A1 (0.45) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL9464278 | 0.82 | ALDH1A1 (0.53) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594569-A1 | PREPARATION OF S-(-)- AND R-(+)-N-(QUINUCLIDINYL-3)-AMIDE | CHIRON LABORATORIES A/S (NO) | 1994-05-04 | — | — | EP | disclosed |
| US-5290938-A | Preparation of S-(-)- and R-(+)-N-(quinuclidinyl-3)-amide | CHIRON LABORATORIES A.S. (NO) | 1994-03-01 | — | — | US | disclosed |
| WO-1991004253-A1 | PREPARATION OF S-(-)- AND R-(+)-N-(QUINUCLIDINYL-3)-AMIDE | CHIRON LABORATORIES A.S (NO) | 1991-04-04 | — | — | WO | disclosed |