Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14611984 | 1.00 | CHRM1 (0.45) | CHRM1ALDH1A1CA12CA1CA2 | |
| SCHEMBL14611983 | 1.00 | CHRM1 (0.45) | CHRM1ALDH1A1CA12CA1CA2 | |
| SCHEMBL14611982 | 1.00 | CHRM1 (0.45) | CHRM1ALDH1A1CA12CA1CA2 | |
| SCHEMBL9304582 | 0.91 | CA12 (0.50) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL9304362 | 0.91 | CA12 (0.50) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL9305195 | 0.91 | CA12 (0.50) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL12396390 | 0.78 | ALDH1A1 (0.48) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL8324789 | 0.76 | CHRM1 (0.45) | CHRM1CA12CA1CA2CA9 | |
| SCHEMBL8312751 | 0.76 | CHRM1 (0.45) | CHRM1CA12CA1CA2CA9 | |
| SCHEMBL10280321 | 0.76 | CHRM3 (0.48) | CHRM1ALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176198-B2 | 1H-pyrazole and 1H-pyrrole-azabicyclic compounds for the treatment of disease | PFIZER INC. (US) | 2007-02-13 | — | — | US | disclosed |