Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16168121 | 0.86 | ALDH1A1 (0.50) | MEN1KMT2AAGTR1ALDH1A1KDM4E | |
| SCHEMBL1483484 | 0.79 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1GAACA12 | |
| SCHEMBL2984483 | 0.77 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL1499127 | 0.77 | AGTR1 (0.60) | PKMMEN1KMT2AAGTR1ALDH1A1 | |
| SCHEMBL10776454 | 0.77 | CA12 (0.59) | GAACA12CA1CA2CA7 | |
| SCHEMBL4629588 | 0.76 | EGFR (0.49) | MEN1KMT2AALDH1A1KDM4ECA12 | |
| SCHEMBL27622551 | 0.75 | EGFR (0.44) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL20631799 | 0.75 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1KDM4EGLA | |
| SCHEMBL7806435 | 0.72 | KDM5A (0.45) | PKMMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL179756 | 0.72 | CAMK2A (0.48) | MEN1KMT2AALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283182-A | Hydrolysis of 5-phenyl hydantoin; yields D(-)phenyl glycine or N-carbamoyl derivative; separation; recycling | BEECHAM GROUP PLC (GB) | 1994-02-01 | — | — | US | claimed |
| US-5283182-A | Hydrolysis of 5-phenyl hydantoin; yields D(-)phenyl glycine or N-carbamoyl derivative; separation; recycling | BEECHAM GROUP PLC (GB) | 1994-02-01 | — | — | US | disclosed |
| EP-0261836-B1 | IMMOBILISED ENZYME PREPARATION AND ITS USE | BEECHAM GROUP PLC (GB) | 1993-07-14 | — | — | EP | disclosed |
| EP-0261836-A1 | Immobilised enzyme preparation and its use | BEECHAM GROUP PLC (GB) | 1988-03-30 | — | — | EP | disclosed |