Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | LIPE | Q05469 | 10/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.49 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9267594 | 0.85 | LMNA (0.63) | LMNALIPEMAPK1RAB9AMAPT | |
| SCHEMBL16839900 | 0.84 | LMNA (0.54) | LMNALIPEMAPK1RAB9ASCN9A | |
| SCHEMBL8413343 | 0.84 | SMN1; SMN2 (0.62) | LMNALIPERAB9AMAPTNPSR1 | |
| SCHEMBL4317357 | 0.83 | LMNA (0.75) | LMNALIPEMAPK1RAB9ASCN9A | |
| SCHEMBL4899851 | 0.83 | LMNA (0.47) | LMNALIPEMAPK1RAB9ASCN9A | |
| SCHEMBL8410496 | 0.83 | LMNA (0.60) | LMNALIPERAB9AMAPTNPSR1 | |
| SCHEMBL9108246 | 0.81 | LMNA (0.63) | LMNALIPEMAPK1RAB9ASCN9A | |
| SCHEMBL1045007 | 0.80 | MAPT (0.56) | LMNAMAPTNPSR1 | |
| SCHEMBL10938287 | 0.80 | LMNA (0.55) | LMNALIPEMAPK1RAB9ASCN9A | |
| SCHEMBL16838951 | 0.80 | LMNA (0.55) | LMNALIPEMAPK1RAB9ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326766-A | Fungicide, nematocide, insecticide, miticide | DOWELANCO | 1994-07-05 | — | — | US | disclosed |
| CN-1083810-A | 4-[2-(4-(2-pyridine oxygen) phenyl) oxyethyl group] quinazoline and analogue thereof | DOWELANCO (US) | 1994-03-16 | — | — | CN | disclosed |
| WO-1994004526-A1 | 4-[2-(4-(2-PYRIDINYLOXY)PHENYL)ETHOXY]-QUINAZOLINE AND ANALOGUES THEREOF | DOWELANCO (US) | 1994-03-03 | — | — | WO | disclosed |