Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | LIPE | Q05469 | 12/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.53 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.53 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.53 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.53 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413343 | 0.88 | SMN1; SMN2 (0.62) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL9267594 | 0.87 | LMNA (0.63) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL9304488 | 0.83 | LMNA (0.58) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL5647580 | 0.82 | LIPE (0.65) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL31143143 | 0.82 | MAPT (0.57) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL7937160 | 0.82 | LIPE (0.59) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL9108593 | 0.82 | MAPT (0.57) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL11351938 | 0.81 | MAPT (0.69) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL876080 | 0.80 | LIPE (0.57) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL7943027 | 0.79 | THRB (0.58) | LMNARAB9ALIPEMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822930-B1 | PYRIDINE DERIVATIVE AND PESTICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5763463-A | Pyridine compounds which are useful as pesticides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0822930-A1 | PYRIDINE DERIVATIVE AND PESTICIDE | KumaiI Chemical Industry Co., Ltd. (JP) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996033975-A1 | PYRIDINE DERIVATIVE AND PESTICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-10-31 | — | — | WO | disclosed |