SCHEMBL9304638

SCHEMBL9304638

COC(=O)C(C)OC(=O)CO

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KLK7 P49862 6/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CA14 Q9ULX7 2/20 0.35
TSHR P16473 4/20 0.35
TDP1 Q9NUW8 1/20 0.34
CA12 O43570 1/20 0.33
MME P08473 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MGAM O43451 2/20 0.32
GAA P10253 2/20 0.32
SI P14410 2/20 0.32
MGAM2 Q2M2H8 2/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetramethylammonium Ion SCHEMBL9710121 0.92 KLK7 (0.35) KLK7SMN1; SMN2CA14TSHRTDP1
SCHEMBL18622831 0.82 KLK7 (0.32) KLK7TSHR
SCHEMBL4673030 0.82 SMN1; SMN2 (0.38) KLK7SMN1; SMN2CA14TSHRCA12
SCHEMBL18179093 0.82 ADRA2A (0.32) KLK7TSHR
SCHEMBL13876099 0.80 MGAM (0.41) TSHRTDP1KMT2AMGAMGAA
SCHEMBL7817942 0.80 SMN1; SMN2 (0.37) KLK7SMN1; SMN2CA14TSHRTDP1
SCHEMBL2886194 0.80 MGAM (0.52) KLK7SMN1; SMN2CA14TSHRTDP1
SCHEMBL2896443 0.80 MGAM (0.52) KLK7SMN1; SMN2CA14TSHRTDP1
SCHEMBL18127581 0.80 LMNA (0.48) TSHRMEN1KMT2A
SCHEMBL2886197 0.80 MGAM (0.52) KLK7SMN1; SMN2CA14TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170107306-A1 ALKOXYSILANE-FUNCTIONALIZED HYDROCARBON COMPOUNDS, INTERMEDIATES THEREOF AND METHODS OF PREPARATION THEREOF HENKEL CORPORATION 2017-04-20 US disclosed
US-5371001-A Transesterification in the presence of carboxy-esterases or carboxyamidases E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-12-06 US disclosed
US-5326887-A Reacting ester of alpha hydroxy acid oligomer over fixed bed catalyst E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-07-05 US disclosed
US-5254718-A Using enzyme catalyst; simplified separation, purification E. I. DU PONT DE NEMOURS & COMPANY (US) 1993-10-19 US disclosed
WO-1992015572-A1 PROCESS FOR THE PREPARATION OF 1,4-DIOXANE-2,5-DIONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-09-17 WO disclosed