SCHEMBL9304739

SCHEMBL9304739

CC(C(=O)O)C(C)(Br)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
TP53 P04637 1/20 0.36
TSHR P16473 1/20 0.36
MAPT P10636 1/20 0.32
PTGS1 P23219 1/20 0.32
THRB P10828 1/20 0.32
RECQL P46063 1/20 0.32
SLC7A5 Q01650 1/20 0.31
CYP2C19 P33261 1/20 0.30
CYP2D6 P10635 2/20 0.30
CYP2C9 P11712 1/20 0.30
HIF1A Q16665 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5478778 0.78
SCHEMBL6910163 0.78
SCHEMBL9207861 0.77 KCNN4 (0.36) TP53MAPT
SCHEMBL8000176 0.77 TP53 (0.31) TP53
SCHEMBL5388712 0.76
SCHEMBL4446324 0.76
SCHEMBL27593632 0.75
SCHEMBL11680928 0.74 ALDH1A1 (0.38) ALDH1A1TP53TSHRMAPTPTGS1
SCHEMBL4792720 0.74
SCHEMBL9356336 0.73 CYP2C19 (0.43) ALDH1A1TP53TSHRTHRBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5347008-A Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents CIBA-GEIGY CORPORATION (US) 1994-09-13 US disclosed
US-5152929-A Corrosion inhibitors for water systems CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed