Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207861 | 0.83 | KCNN4 (0.36) | TP53 | |
| SCHEMBL9304739 | 0.77 | ALDH1A1 (0.36) | TP53 | |
| SCHEMBL3138263 | 0.68 | ALDH1A1 (0.33) | TP53 | |
| SCHEMBL27593632 | 0.68 | — | — | |
| SCHEMBL13017004 | 0.68 | — | — | |
| SCHEMBL4864614 | 0.67 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL23203394 | 0.65 | TP53 (0.35) | TP53 | |
| SCHEMBL13970291 | 0.65 | ALDH1A1 (0.36) | TP53 | |
| SCHEMBL125061 | 0.65 | — | — | |
| SCHEMBL2631496 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6083975-A | ADMINISTERING TO THE PATIENTS A SUBSTITUTED 5-(2-((2-ARYL-2-HYDROXYETHYL)AMINO)ALKYL)-1,4-BENZODIOXIN DICARBONYL COMPOUNDS AS ANTIOBESITY AGENT | AMERICAN HOME PRODUCTS (US) | 2000-07-04 | — | — | US | disclosed |
| US-6020361-A | ANTIDIABETIC AGENT, HYPOGLYCEMIC AGENT | AMERICA HOME PRODUCTS CORP. (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0948494-A1 | SUBSTITUTED BENZO 1,4]DIOXANES AS ANTIOBESITY AGENTS | American Home Products Corporation (US) | 1999-10-13 | — | — | EP | disclosed |
| US-5965607-A | FOR TREATING DIABETES AND/OR HYPERGLYCEMIA AND/OR OBESITY IN MAMMALS AND PRODUCING LEAN MEAT IN EDIBLE DOMESTIC ANIMALS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| WO-1998029405-A1 | SUBSTITUTED BENZO[1,4]DIOXANES AS ANTIOBESITY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-07-09 | — | — | WO | disclosed |