Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MC5R | P33032 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10863100 | 0.80 | MC4R (0.35) | MC4RMC5RHRH3CA12CA6 | |
| SCHEMBL7992705 | 0.79 | VHL (0.41) | MC4RMC5RHRH3IGF1RMEN1 | |
| SCHEMBL10862922 | 0.79 | MC4R (0.34) | MC4RMC5RHRH3CA12CA6 | |
| SCHEMBL10865896 | 0.79 | SIGMAR1 (0.34) | MC4RMC5RHRH3NOTUMCA12 | |
| SCHEMBL10862013 | 0.78 | HRH3 (0.47) | MC4RMC5RHRH3CHRM1ALDH1A1 | |
| SCHEMBL10864820 | 0.76 | EPHX2 (0.43) | MC4RMC5RHRH3IGF1RKMT2A | |
| SCHEMBL10864880 | 0.76 | HRH3 (0.34) | MC4RMC5RHRH3ALDH1A1JAK2 | |
| SCHEMBL10864502 | 0.75 | EPHX2 (0.44) | MC4RMC5RIGF1RALDH1A1LMNA | |
| SCHEMBL10865941 | 0.75 | CACNA1G (0.32) | MC4RMC5RHRH3 | |
| SCHEMBL10863059 | 0.75 | MC4R (0.32) | MC4RMC5RHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360906-A | N-(3-halo-5-isoxazolylmethyl)-2-nitromethylene- and -2-nitroimino-imidazolines and pyrimidines; aminoalkylation, cyclization | SHELL RESEARCH LIMITED (GB) | 1994-11-01 | — | — | US | disclosed |
| EP-0555931-A1 | Isoxazole derivatives and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-08-18 | — | — | EP | disclosed |
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |