Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | PDE6D | O43924 | 1/20 | 0.52 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.52 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.52 |
| ▸ | TNF | P01375 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22001014 | 0.83 | TP53 (0.57) | RAB9AL3MBTL1ALDH1A1TNFLMNA | |
| SCHEMBL9304572 | 0.83 | RAB9A (0.51) | CYP19A1RAB9AALDH1A1LMNAMEN1 | |
| SCHEMBL4834224 | 0.83 | TNF (0.44) | CYP19A1RAB9AALDH1A1TNFKMT2A | |
| SCHEMBL1264013 | 0.83 | ESR1 (0.44) | CYP19A1RAB9AALDH1A1PDE6DALDH2 | |
| SCHEMBL15243034 | 0.79 | CYP19A1 (0.56) | CYP19A1RAB9AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL4094595 | 0.79 | CYP19A1 (0.56) | CYP19A1RAB9AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL9304138 | 0.78 | TSHR (0.54) | RAB9AL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL29234887 | 0.78 | CXCR2 (0.47) | ALDH1A1LMNAKMT2AKDM4ETP53 | |
| SCHEMBL31607620 | 0.77 | CYP11B1 (0.54) | RAB9AL3MBTL1ALDH1A1PDE6DALDH2 | |
| SCHEMBL4833321 | 0.76 | CFTR (0.53) | CYP19A1ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374701-A | Crosslinkable polymers of high strength free of structural defects | HAY ALLAN S (CA) | 1994-12-20 | — | — | US | disclosed |
| US-5233046-A | DIARYLACETYLENES, ENAMINES AND ACETYLENIC POLYMERS AND THEIR PRODUCTION | HAY ALLAN S (CA) | 1993-08-03 | — | — | US | disclosed |
| WO-1993009079-A1 | DIARYLACETYLENES, ENAMINES AND ACETYLENIC POLYMERS AND THEIR PRODUCTION | HAY ALAN S (CA) | 1993-05-13 | — | — | WO | disclosed |