Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PAM | P19021 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868974 | 0.82 | KMT2A (0.47) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL10487933 | 0.80 | GAA (0.48) | KMT2ATSHRHSD17B10 | |
| SCHEMBL6114729 | 0.79 | KMT2A (0.61) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL9309031 | 0.79 | KMT2A (0.61) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL2439083 | 0.78 | CA2 (0.61) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL8746194 | 0.77 | KMT2A (0.53) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL31314673 | 0.76 | KMT2A (0.45) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL28423222 | 0.76 | KMT2A (0.41) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL2721428 | 0.76 | KMT2A (0.57) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL3978412 | 0.76 | CA2 (0.59) | KMT2ACA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5372820-A | Materials capable of binding biological substances, and its applications, in particular, as in an affinity chromatography support | THERAPEUTIQUES SUBTITUTIVES GROUPEMENT D'INTERET PUBLIC (FR) | 1994-12-13 | — | — | US | disclosed |
| EP-0357479-B1 | MATERIAL, CAPABLE OF FIXING BIOLOGICAL SUBSTANCES AND ITS USE ESPECIALLY AS SUPPORT FOR AFFINITY CHROMATOGRAPHY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1992-04-15 | — | — | EP | disclosed |
| EP-0357479-A1 | Material, capable of fixing biological substances and its use especially as support for affinity chromatography | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1990-03-07 | — | — | EP | disclosed |