Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | ACR | P10323 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305421 | 0.93 | HSD17B10 (0.52) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9306527 | 0.88 | HSD17B10 (0.51) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL7591660 | 0.87 | LMNA (0.75) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL12608584 | 0.87 | LMNA (0.75) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL12633724 | 0.87 | LMNA (0.75) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9666088 | 0.87 | LMNA (0.75) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9305136 | 0.86 | SENP1 (0.49) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9303831 | 0.85 | KMT2A (0.59) | CYP1A2CYP2C9SMN1; SMN2KMT2AMAPT | |
| SCHEMBL17734118 | 0.84 | CA1 (0.77) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL28560938 | 0.84 | CA1 (0.77) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5277838-A | Silylated benzoic acid derivatives | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-01-11 | — | — | US | disclosed |