Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28625721 | 0.86 | HCAR2 (0.45) | HCAR2ALDH1A1SOAT1MDM4LMNA | |
| SCHEMBL2609725 | 0.86 | HCAR2 (0.45) | HCAR2ALDH1A1SOAT1MDM4LMNA | |
| SCHEMBL28404629 | 0.81 | ALDH1A1 (0.60) | HCAR2ALDH1A1SOAT1LMNAMAPT | |
| SCHEMBL2897728 | 0.80 | HCAR2 (0.59) | HCAR2ALDH1A1LMNAMAPTGAA | |
| SCHEMBL2114194 | 0.80 | HCAR2 (0.70) | HCAR2ALDH1A1MAPTGAAATM | |
| SCHEMBL4880509 | 0.80 | HCAR2 (0.59) | HCAR2ALDH1A1LMNAMAPTGAA | |
| SCHEMBL1965839 | 0.80 | HCAR2 (0.70) | HCAR2ALDH1A1MAPTGAAATM | |
| SCHEMBL20562242 | 0.79 | HCAR2 (0.62) | HCAR2ALDH1A1MDM4LMNAMAPT | |
| SCHEMBL20561334 | 0.79 | HCAR2 (0.62) | HCAR2ALDH1A1MDM4LMNAMAPT | |
| SCHEMBL20562241 | 0.79 | HCAR2 (0.62) | HCAR2ALDH1A1MDM4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352692-A | Thiophene-2-carboxylic acid derivatives | LAEVOSAN GESELLSCHAFT M. B. H. (AT) | 1994-10-04 | — | — | US | claimed |
| US-5352692-A | Thiophene-2-carboxylic acid derivatives | LAEVOSAN GESELLSCHAFT M. B. H. (AT) | 1994-10-04 | — | — | US | disclosed |