Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | MITF | O75030 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | ACHE | P22303 | 5/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | IKBKB | O14920 | 1/20 | 0.58 |
| ▸ | RAF1 | P04049 | 1/20 | 0.58 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.58 |
| ▸ | AKT1 | P31749 | 1/20 | 0.58 |
| ▸ | AKT2 | P31751 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.58 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.58 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305010 | 1.00 | MAPT (0.66) | MAPTHTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL22822883 | 1.00 | MAPT (0.66) | MAPTHTTLMNASMN1; SMN2RAB9A | |
| Dimethylamine SCHEMBL8372694 | 0.95 | MAPT (0.60) | MAPTHTTLMNASMN1; SMN2RAB9A | |
| Diethylamine SCHEMBL8377295 | 0.89 | MAPT (0.55) | MAPTHTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL22550766 | 0.83 | ACHE (0.64) | MAPTHTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL31518789 | 0.83 | ACHE (0.64) | MAPTHTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL24733669 | 0.83 | MAPT (0.49) | MAPTHTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL17899562 | 0.81 | DRD3 (0.66) | MAPTHTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL13036875 | 0.81 | HTT (0.67) | MAPTHTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL11608460 | 0.81 | ACHE (0.62) | MAPTHTTLMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332819-A | Photobleachable initiator systems | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-26 | — | — | US | disclosed |
| US-5217846-A | Photopolymerizable compostion containing an addition polymerizable unsaturated initiator, a coinitiater and a sensitizer | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-08 | — | — | US | disclosed |
| US-4085102-A | CNS DEPRESSANTS, MUSCLE RELAXANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-04-18 | — | — | US | disclosed |
| US-4065617-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1977-12-27 | — | — | US | disclosed |