Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23467914 | 0.84 | GAA (0.69) | GAACA12CA1CA2CA9 | |
| SCHEMBL8927097 | 0.79 | GAA (0.50) | GAACA12CA1CA2CA9 | |
| SCHEMBL8391028 | 0.78 | ALDH1A1 (0.51) | ALDH1A1LMNATSHRCYP3A4THRB | |
| SCHEMBL9305685 | 0.77 | GAA (0.48) | GAACA12CA1CA2CA9 | |
| SCHEMBL6644742 | 0.74 | CA1 (0.45) | CA1CA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3488898 | 0.72 | SMN1; SMN2 (0.61) | TSHRSMN1; SMN2TDP1EPHX2 | |
| SCHEMBL8890921 | 0.70 | CA12 (0.45) | GAACA12CA1CA2CA9 | |
| SCHEMBL9225785 | 0.70 | RAB9A (0.50) | GAACA12CA1CA2CA9 | |
| SCHEMBL13323567 | 0.70 | GAA (0.49) | GAACA12CA1CA2CA9 | |
| SCHEMBL24568195 | 0.70 | SMN1; SMN2 (0.56) | GAACYP3A4CYP2C19SMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364780-A | Genetic engineering with DNA and promoters | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-11-15 | — | — | US | claimed |
| EP-0463056-A1 | EXTERNAL REGULATION OF GENE EXPRESSION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-02 | — | — | EP | claimed |
| WO-1990011361-A1 | EXTERNAL REGULATION OF GENE EXPRESSION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-04 | — | — | WO | claimed |
| EP-0388186-A1 | External regulation of gene expression | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-09-19 | — | — | EP | claimed |