Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305038 | 0.75 | DPP4 (0.34) | FABP3FABP4SMN1; SMN2CCNB2CDK1 | |
| SCHEMBL31643743 | 0.69 | CYP3A4 (0.43) | CYP3A4ACHEP2RX3MEN1KMT2A | |
| SCHEMBL31643549 | 0.68 | MEN1 (0.37) | PPARGSMN1; SMN2CYP3A4ACHEPLA2G2A | |
| SCHEMBL10186774 | 0.65 | KMT2A (0.33) | SMN1; SMN2CYP3A4ACHEP2RX3MEN1 | |
| SCHEMBL12772067 | 0.65 | CYP3A4 (0.55) | SMN1; SMN2CYP3A4ACHEMEN1KMT2A | |
| SCHEMBL12553004 | 0.64 | MEN1 (0.37) | SMN1; SMN2CYP3A4ACHEMEN1KMT2A | |
| SCHEMBL29034603 | 0.63 | PDE4B (0.40) | FABP3FABP4PRNPPPARGRXFP1 | |
| SCHEMBL10187364 | 0.62 | KMT2A (0.33) | FABP3FABP4CYP3A4ACHEP2RX3 | |
| SCHEMBL9637066 | 0.62 | PTGS2 (0.50) | SMN1; SMN2LMNA | |
| SCHEMBL10187365 | 0.62 | KMT2A (0.34) | FABP3FABP4SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281720-A | Antiasthmatics, antiallergens, antiinflammatory agents and cytoprotective agents | MERCK FROSST CANADA, INC. | 1994-01-25 | — | — | US | disclosed |
| EP-0501578-A1 | Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA INC. (CA) | 1992-09-02 | — | — | EP | disclosed |