Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | FABP3 | P05413 | 3/20 | 0.37 |
| ▸ | FABP4 | P15090 | 3/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29034610 | 0.84 | TDP1 (0.40) | PRNPLMNATACR1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4882804 | 0.73 | PREP (0.50) | PRNPPPARGRXFP1NR2E3NCOR2 | |
| SCHEMBL29034599 | 0.71 | BACE1 (0.43) | LMNASMN1; SMN2POLBGPR35KDM4E | |
| SCHEMBL4387282 | 0.67 | PRNP (0.42) | PRNPPPARGRXFP1NR2E3NCOR2 | |
| SCHEMBL4882805 | 0.67 | P2RX3 (0.35) | PREPSMN1; SMN2POLBL3MBTL1KDM4E | |
| SCHEMBL4922175 | 0.67 | ERCC1 (0.43) | POLBMAPTDHODHGABRA2GABRB2 | |
| SCHEMBL29034602 | 0.66 | GPR35 (0.44) | GPR35KDM4EALDH1A1HPGDPTGS2 | |
| SCHEMBL7622495 | 0.65 | BACE1 (0.44) | PREPSMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL2356942 | 0.65 | AKT2 (0.36) | PREPLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL29034601 | 0.65 | BACE1 (0.41) | SMN1; SMN2POLBGPR35MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108472381-B | Compounds and therapeutic uses thereof | 森陶里治疗有限公司 | 2023-06-06 | — | — | CN | disclosed |