Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10348751 | 0.86 | ALDH1A1 (0.38) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL11797094 | 0.85 | CYP1A2 (0.47) | ALDH1A1GAAPKMALOX15HSD17B10 | |
| SCHEMBL144821 | 0.85 | CA2 (0.50) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL10348753 | 0.82 | CNR1 (0.38) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL11878097 | 0.81 | GAA (0.56) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL9306002 | 0.79 | HDAC4 (0.33) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL10717693 | 0.77 | AKR1C3 (0.40) | ALDH1A1HPGDHSD17B10TSHRCYP2C9 | |
| SCHEMBL11618550 | 0.77 | NPC1 (0.43) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL2951999 | 0.76 | CYP1A2 (0.44) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL9188294 | 0.76 | CA2 (0.41) | ALDH1A1GAAUSP2HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308901-A | Oxidation resistant, photostabilizers for polymers | GENERAL ELECTRIC COMPANY (US) | 1994-05-03 | — | — | US | disclosed |
| US-5137950-A | Reacting phosphorous trichloride with alcohol; polymer stabilizer | BORG-WARNER SPECIALTY CHEMICALS, INC. (US) | 1992-08-11 | — | — | US | disclosed |