Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.37 |
| ▸ | TUBB | P07437 | 2/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685052 | 0.91 | TDP1 (0.60) | TDP1LMNAAPEX1CES2CES1 | |
| SCHEMBL5249714 | 0.86 | LMNA (0.53) | TDP1LMNAAPEX1CES2CES1 | |
| SCHEMBL8956285 | 0.82 | LMNA (0.42) | TDP1LMNAPTGESALOX5PPARG | |
| SCHEMBL2042270 | 0.82 | LMNA (0.49) | TDP1LMNAAPEX1CES2CES1 | |
| SCHEMBL9785974 | 0.81 | LMNA (0.48) | TDP1LMNAAPEX1CES2CES1 | |
| SCHEMBL3082168 | 0.81 | LMNA (0.48) | TDP1LMNAAPEX1CES2CES1 | |
| SCHEMBL15402372 | 0.80 | TDP1 (0.60) | TDP1LMNAAPEX1CES2CES1 | |
| SCHEMBL3250732 | 0.80 | TDP1 (0.67) | TDP1LMNAAPEX1CES2CES1 | |
| SCHEMBL5467260 | 0.80 | TDP1 (0.67) | TDP1LMNAAPEX1CES2CES1 | |
| SCHEMBL489897 | 0.80 | TDP1 (0.67) | TDP1LMNAAPEX1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302486-A | Encapsulated toner process utilizing phase separation | XEROX CORPORATION (US) | 1994-04-12 | — | — | US | disclosed |