Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PGD | P52209 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1595064 | 1.00 | SUCNR1 (0.45) | SUCNR1MAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL27159744 | 1.00 | SUCNR1 (0.45) | SUCNR1MAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL10473227 | 1.00 | SUCNR1 (0.45) | SUCNR1MAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL1727954 | 1.00 | SUCNR1 (0.45) | SUCNR1MAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL18219198 | 0.90 | SUCNR1 (0.38) | SUCNR1MAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL18219558 | 0.90 | SUCNR1 (0.38) | SUCNR1MAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL13997318 | 0.87 | SUCNR1 (0.39) | SUCNR1MAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL26678742 | 0.87 | SUCNR1 (0.39) | SUCNR1MAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL14007051 | 0.87 | SUCNR1 (0.39) | SUCNR1MAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL5048000 | 0.87 | SUCNR1 (0.39) | SUCNR1MAPK1NPSR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190008991-A1 | MALODOR REDUCTION COMPOSITIONS | THE PROCTER & GAMBLE COMPANY | 2019-01-10 | — | — | US | claimed |
| EP-3424539-A1 | MALODOR REDUCTION COMPOSITIONS | The Procter & Gamble Company (US) | 2019-01-09 | — | — | EP | claimed |
| US-6143379-A | Polymer laminates having increased hiding power | CLARIANT GMBH (DE) | 2000-11-07 | — | — | US | claimed |
| EP-3704120-B1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | JUBILANT EPISCRIBE LLC (US) | 2024-03-06 | — | — | EP | disclosed |
| US-20210371431-A1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | JUBILANT EPISCRIBE LLC | 2021-12-02 | — | — | US | disclosed |
| US-11168097-B2 | Photochemical methods of making cyclobutane boronates and related compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2021-11-09 | — | — | US | disclosed |
| US-11020386-B2 | Methods and compositions for preventing opioid abuse | ALBANY MOLECULAR RESEARCH, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| US-11020386-B2 | Methods and compositions for preventing opioid abuse | ALBANY MOLECULAR RESEARCH, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| EP-3704120-A1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | Jubilant Episcribe LLC (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10765648-B2 | iNKT cell modulators and methods of using the same | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 2020-09-08 | — | — | US | disclosed |
| CN-111542523-A | Heterocyclic compounds as PRMT5 inhibitors | 朱比连特埃皮斯科瑞有限责任公司 | 2020-08-14 | — | — | CN | disclosed |
| US-6143379-A | Polymer laminates having increased hiding power | CLARIANT GMBH (DE) | 2000-11-07 | — | — | US | disclosed |
| US-5613494-A | ULTRASONIC CONTRAST AGENT, MICROPARTICLES CONTAINING A GAS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-25 | — | — | US | disclosed |
| US-5505784-A | Polycondensates which contain tartaric acid derivatives, processes for their preparation and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-09 | — | — | US | disclosed |
| US-5391696-A | Biodegradable polyesters and polyamides for sustained drug delivery and as ultrasonic contrast agents in medical diagnosis, particularly blood circulation of the heart | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-02-21 | — | — | US | disclosed |
| US-5142099-A | Hemicaronic aldehyde intermediates | ROUSSEL UCLAF (FR) | 1992-08-25 | — | — | US | disclosed |
| US-5047557-A | Complexes having optically active ligands, a process for their preparation and their use | CIBA-GEIGY CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |
| US-4996349-A | Reducing dioxolane diester to dialdehyde, adding ester using organic phosphorus compound, reacting with gem-dimethylcyclo-propanation reagent, hydrolyzing, cleaving | ROUSSEL UCLAF (FR) | 1991-02-26 | — | — | US | disclosed |
| US-4942227-A | ANTITUMOR AGENTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1990-07-17 | — | — | US | disclosed |
| EP-0305289-A1 | Enantioselective process for preparing derivatives of trans- or cis-hemicaronaldehyde, and intermediates obtained | ROUSSEL-UCLAF (FR) | 1989-03-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10765648-B2 | iNKT cell modulators and methods of using the same | PBK, NFATC1, UGCG | SUCNR1 2721/4885MAPK1 4336/4885NPSR1 2394/4885 |
| US-11020386-B2 | Methods and compositions for preventing opioid abuse | OPRM1, OPRK1, OPRD1 | SUCNR1 1109/4885MAPK1 4617/4885NPSR1 92/4885 |
| US-11168097-B2 | Photochemical methods of making cyclobutane boronates and related compounds | BLVRB, CYP11B2, CYP11B1 | SUCNR1 747/4885MAPK1 1889/4885NPSR1 2133/4885 |
| US-20210371431-A1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | PRMT5, PRMT1, PRMT3 | SUCNR1 1854/4885MAPK1 576/4885NPSR1 4120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.