Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307036 | 0.85 | CYP2D6 (0.47) | CYP2D6TSHRAMY1ACYP2C19CYP3A4 | |
| SCHEMBL3810884 | 0.82 | CYP2D6 (0.59) | CYP2D6TSHRAMY1ACYP2C19CYP3A4 | |
| SCHEMBL1345214 | 0.82 | CYP2D6 (0.59) | CYP2D6TSHRAMY1ACYP2C19CYP3A4 | |
| SCHEMBL1345705 | 0.82 | CYP2D6 (0.59) | CYP2D6TSHRAMY1ACYP2C19CYP3A4 | |
| SCHEMBL3819212 | 0.82 | CYP2D6 (0.59) | CYP2D6TSHRAMY1ACYP2C19CYP3A4 | |
| SCHEMBL1345527 | 0.82 | CYP2D6 (0.59) | CYP2D6TSHRAMY1ACYP2C19CYP3A4 | |
| SCHEMBL3821963 | 0.82 | CYP2D6 (0.59) | CYP2D6TSHRAMY1ACYP2C19CYP3A4 | |
| SCHEMBL1343857 | 0.82 | CYP2D6 (0.59) | CYP2D6TSHRAMY1ACYP2C19CYP3A4 | |
| SCHEMBL9307031 | 0.82 | CYP2D6 (0.55) | CYP2D6TSHRAMY1ACYP2C19CYP3A4 | |
| SCHEMBL9305110 | 0.82 | AMY1A (0.66) | AMY1ACYP2C19CYP3A4CYP2C9HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376498-A | Blend of an alkali-soluble resin, compound that generates an acid upon irradiation, functional aromatic compound and a phenolic compound | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| EP-0542572-A1 | Negative type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |