Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308207 | 1.00 | THRA (0.67) | THRATHRBALDH1A1HPGDPLA2G2D | |
| SCHEMBL9307582 | 0.89 | THRA (0.70) | THRATHRBALDH1A1HPGDPLA2G2D | |
| SCHEMBL9307228 | 0.89 | THRA (0.70) | THRATHRBALDH1A1HPGDPLA2G2D | |
| SCHEMBL9306887 | 0.85 | THRA (0.65) | THRATHRBSMPD1 | |
| SCHEMBL9306905 | 0.85 | THRA (0.65) | THRATHRBSMPD1 | |
| SCHEMBL7020183 | 0.84 | SMPD1 (0.60) | THRATHRBALDH1A1HPGDPLA2G2D | |
| SCHEMBL9307706 | 0.84 | SMPD1 (0.60) | THRATHRBALDH1A1HPGDPLA2G2D | |
| SCHEMBL9307466 | 0.84 | SMPD1 (0.60) | THRATHRBALDH1A1HPGDPLA2G2D | |
| SCHEMBL8644866 | 0.82 | THRA (0.64) | THRATHRBALDH1A1HPGDPLA2G2D | |
| SCHEMBL9307742 | 0.82 | THRA (0.67) | THRATHRBALDH1A1HPGDPLA2G2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5208247-A | Antianaphylactic agents or septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530444-A1 | Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |