Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 6/20 | 0.60 |
| ▸ | THRA | P10827 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307466 | 1.00 | SMPD1 (0.60) | SMPD1THRATHRBALDH1A1HPGD | |
| SCHEMBL9307706 | 1.00 | SMPD1 (0.60) | SMPD1THRATHRBALDH1A1HPGD | |
| SCHEMBL8420304 | 0.94 | SMPD1 (0.52) | SMPD1THRATHRBALDH1A1HPGD | |
| SCHEMBL9306797 | 0.93 | THRA (0.65) | SMPD1THRATHRBHPGDPLA2G4B | |
| SCHEMBL9578512 | 0.93 | THRA (0.65) | SMPD1THRATHRBHPGDPLA2G4B | |
| SCHEMBL9308281 | 0.93 | SMPD1 (0.71) | SMPD1THRATHRBCNR2PLA2G4B | |
| SCHEMBL8644866 | 0.88 | THRA (0.64) | SMPD1THRATHRBALDH1A1HPGD | |
| SCHEMBL11321553 | 0.88 | THRA (0.67) | SMPD1THRATHRBALDH1A1HPGD | |
| SCHEMBL9626799 | 0.88 | THRA (0.67) | SMPD1THRATHRBALDH1A1HPGD | |
| SCHEMBL11315387 | 0.88 | THRA (0.67) | SMPD1THRATHRBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1277790-A2 | Nucleators for crystallizable thermoplastic polymers | Ciba SC Holding AG (CH) | 2003-01-22 | — | — | EP | disclosed |
| EP-0940431-A1 | Nucleators for crystallizable thermoplastic polymers | Universität Bayreuth (DE) | 1999-09-08 | — | — | EP | disclosed |