Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972660 | 0.83 | SMN1; SMN2 (0.47) | ALDH1A1GAAL3MBTL1RAB9ANPC1 | |
| SCHEMBL9304858 | 0.83 | RAB9A (0.52) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9305602 | 0.81 | GAA (0.44) | ALDH1A1GAAL3MBTL1RAB9ASLC16A3 | |
| SCHEMBL8973137 | 0.81 | RAB9A (0.43) | RAB9ANPC1MEN1KMT2AELANE | |
| SCHEMBL8972426 | 0.81 | LMNA (0.46) | ALDH1A1GAARAB9ANPC1MEN1 | |
| SCHEMBL10892259 | 0.80 | RAB9A (0.50) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9305778 | 0.79 | RAB9A (0.38) | ALDH1A1GAARAB9ANPC1KMT2A | |
| SCHEMBL10892199 | 0.79 | RAB9A (0.47) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9305334 | 0.79 | RAB9A (0.42) | RAB9ANPC1MEN1KMT2AHDAC6 | |
| SCHEMBL9305589 | 0.79 | RAB9A (0.38) | ALDH1A1GAAL3MBTL1RAB9ASLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |