Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21058237 | 0.77 | TAAR1 (0.54) | LMNAGRM2GRM3TDP1HSD17B10 | |
| SCHEMBL13614221 | 0.77 | S1PR1 (0.62) | S1PR4S1PR1S1PR3S1PR5 | |
| Oxalic Acid SCHEMBL9584402 | 0.76 | GRM2 (0.44) | GRM2GRM3S1PR4S1PR1S1PR3 | |
| SCHEMBL26697028 | 0.76 | LMNA (0.49) | LMNAGRM2GRM3TDP1ALDH1A1 | |
| SCHEMBL9190217 | 0.75 | GRM2 (0.46) | LMNAGRM2GRM3ALDH1A1SMN1; SMN2 | |
| SCHEMBL5428396 | 0.74 | TAAR1 (0.47) | GRM2GRM3S1PR4S1PR1S1PR3 | |
| SCHEMBL6803588 | 0.74 | HDAC3 (0.50) | LMNAGRM2GRM3ALDH1A1SMN1; SMN2 | |
| SCHEMBL9183600 | 0.74 | TAAR1 (0.47) | GRM2GRM3S1PR4S1PR1S1PR3 | |
| SCHEMBL386783 | 0.74 | LMNA (0.39) | LMNAGRM2GRM3S1PR4S1PR1 | |
| SCHEMBL3616371 | 0.73 | GRM2 (0.51) | GRM2GRM3TDP1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364850-A | Analgesics | G. D. SEARLE & CO. (US) | 1994-11-15 | — | — | US | disclosed |