Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 5/20 | 0.40 |
| ▸ | PLG | P00747 | 5/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.40 |
| ▸ | F2 | P00734 | 4/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9304125 | 0.99 | ACHE (0.56) | ACHEDRD2DRD3ARF10 | |
| SCHEMBL9305709 | 0.91 | ACHE (0.55) | ACHEDRD2DRD3F10PLG | |
| Hydrochloric Acid SCHEMBL9305099 | 0.90 | ACHE (0.54) | ACHEDRD2DRD3F10PLG | |
| SCHEMBL9303716 | 0.89 | ACHE (0.53) | ACHEDRD2DRD3F10PLG | |
| Hydrochloric Acid SCHEMBL9306200 | 0.88 | ACHE (0.52) | ACHEDRD2DRD3F10PLG | |
| SCHEMBL9518883 | 0.80 | ACHE (0.58) | ACHEDRD2DRD3HSD17B10ALDH1A1 | |
| SCHEMBL5681817 | 0.80 | ACHE (0.58) | ACHEDRD2DRD3HSD17B10ALDH1A1 | |
| SCHEMBL5679478 | 0.80 | ACHE (0.58) | ACHEDRD2DRD3HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9443687 | 0.79 | ACHE (0.57) | ACHEDRD2DRD3HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8765234 | 0.79 | ACHE (0.57) | ACHEDRD2DRD3HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312961-A | 2-amino-7-hydroxytetralin carboxylalkyl ethers | ELF SANOFI (FR) | 1994-05-17 | — | — | US | claimed |
| EP-0383686-B1 | 2-AMINO-7-HYDROXYTETRALINE CARBOXYALKYL ETHERS | ELF SANOFI (FR) | 1993-08-04 | — | — | EP | claimed |
| EP-0383686-A1 | 2-Amino-7-hydroxytetraline carboxyalkyl ethers | ELF SANOFI (FR) | 1990-08-22 | — | — | EP | claimed |
| US-5312961-A | 2-amino-7-hydroxytetralin carboxylalkyl ethers | ELF SANOFI (FR) | 1994-05-17 | — | — | US | disclosed |
| EP-0383686-B1 | 2-AMINO-7-HYDROXYTETRALINE CARBOXYALKYL ETHERS | ELF SANOFI (FR) | 1993-08-04 | — | — | EP | disclosed |
| EP-0383686-A1 | 2-Amino-7-hydroxytetraline carboxyalkyl ethers | ELF SANOFI (FR) | 1990-08-22 | — | — | EP | disclosed |