Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | STS | P08842 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CTSD | P07339 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50229 | 0.91 | MAPT (0.64) | NPC1MAPTRAB9AALDH1A1HSD17B10 | |
| SCHEMBL29573531 | 0.91 | MAPT (0.64) | NPC1MAPTRAB9AALDH1A1HSD17B10 | |
| Bicarbonate SCHEMBL27740092 | 0.90 | MAPT (0.62) | NPC1MAPTRAB9AALDH1A1HSD17B10 | |
| Benzophenone SCHEMBL11416830 | 0.90 | MAPT (0.67) | NPC1MAPTRAB9AALDH1A1HSD17B10 | |
| Methylene Chloride SCHEMBL28311944 | 0.88 | NPC1 (0.61) | NPC1MAPTRAB9AALDH1A1HSD17B10 | |
| SCHEMBL6616664 | 0.88 | MAPT (0.69) | NPC1MAPTRAB9AALDH1A1HSD17B10 | |
| Water SCHEMBL2857055 | 0.88 | MAPT (0.60) | NPC1MAPTRAB9AALDH1A1HSD17B10 | |
| Acetophenone SCHEMBL12002632 | 0.85 | MAPT (0.57) | NPC1MAPTRAB9AALDH1A1HSD17B10 | |
| SCHEMBL29291422 | 0.83 | TP53 (0.64) | NPC1MAPTRAB9AALDH1A1HSD17B10 | |
| SCHEMBL8439039 | 0.83 | ALDH1A1 (0.64) | NPC1MAPTRAB9AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5331103-A | Reaction with hydrogen peroxide, hydroquinone from phenol | RHONE-POULENC CHIMIE (FR) | 1994-07-19 | — | — | US | disclosed |