Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 9/20 | 0.59 |
| ▸ | FNTB | P49356 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305768 | 1.00 | FNTA (0.59) | FNTAFNTBALDH1A1ALOX15KMT2A | |
| SCHEMBL6579169 | 0.98 | ALOX15 (0.61) | FNTAFNTBALDH1A1ALOX15KMT2A | |
| SCHEMBL6579163 | 0.98 | ALOX15 (0.61) | FNTAFNTBALDH1A1ALOX15KMT2A | |
| Squalene SCHEMBL27829218 | 0.89 | KMT2A (0.63) | FNTAFNTBALDH1A1ALOX15KMT2A | |
| SCHEMBL3269528 | 0.86 | FNTA (0.54) | FNTAFNTBALDH1A1ALOX15KMT2A | |
| SCHEMBL3269523 | 0.86 | FNTA (0.54) | FNTAFNTBALDH1A1ALOX15KMT2A | |
| SCHEMBL5576771 | 0.86 | ALOX15 (0.62) | FNTAFNTBALDH1A1ALOX15KMT2A | |
| SCHEMBL4025176 | 0.85 | FNTA (0.58) | FNTAFNTBALDH1A1ALOX15KMT2A | |
| SCHEMBL30531902 | 0.83 | KMT2A (0.70) | FNTAFNTBALDH1A1ALOX15KMT2A | |
| SCHEMBL6061920 | 0.83 | KMT2A (0.70) | FNTAFNTBALDH1A1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601573-A1 | Alpha-phosphonocarboxylate squalene synthetase inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-15 | — | — | EP | disclosed |
| US-5312814-A | Antilipemic agents or anticholesterol agents | BRISTOL-MYERS SQUIBB CO. (US) | 1994-05-17 | — | — | US | disclosed |