Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | FNTA | P49354 | 6/20 | 0.57 |
| ▸ | FNTB | P49356 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579163 | 1.00 | ALOX15 (0.61) | ALOX15ALDH1A1FNTAFNTBKDM4E | |
| SCHEMBL9305768 | 0.98 | FNTA (0.59) | ALOX15ALDH1A1FNTAFNTBKDM4E | |
| SCHEMBL9305765 | 0.98 | FNTA (0.59) | ALOX15ALDH1A1FNTAFNTBKDM4E | |
| SCHEMBL5576771 | 0.87 | ALOX15 (0.62) | ALOX15ALDH1A1FNTAFNTBKDM4E | |
| Squalene SCHEMBL27829218 | 0.87 | KMT2A (0.63) | ALOX15ALDH1A1FNTAFNTBKDM4E | |
| SCHEMBL3269523 | 0.84 | FNTA (0.54) | ALOX15ALDH1A1FNTAFNTBKDM4E | |
| SCHEMBL3269528 | 0.84 | FNTA (0.54) | ALOX15ALDH1A1FNTAFNTBKDM4E | |
| SCHEMBL3664267 | 0.83 | ALDH1A1 (0.67) | ALOX15ALDH1A1FNTAFNTBTRPV1 | |
| SCHEMBL4025176 | 0.83 | FNTA (0.58) | ALOX15ALDH1A1FNTAFNTBKDM4E | |
| SCHEMBL25266180 | 0.82 | PTGS1 (0.44) | ALOX15ALDH1A1FNTAFNTBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |