Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18243744 | 0.85 | ALDH1A1 (0.57) | CYP1A2CYP2C19CYP2D6POLBLMNA | |
| SCHEMBL8499685 | 0.85 | CYP1A2 (0.48) | CYP1A2CYP2C19CYP2D6POLBLMNA | |
| SCHEMBL8499687 | 0.85 | CYP1A2 (0.48) | CYP1A2CYP2C19CYP2D6POLBLMNA | |
| SCHEMBL10651538 | 0.85 | CYP1A2 (0.48) | CYP1A2CYP2C19CYP2D6POLBLMNA | |
| SCHEMBL10651535 | 0.85 | CYP1A2 (0.48) | CYP1A2CYP2C19CYP2D6POLBLMNA | |
| SCHEMBL16618643 | 0.81 | ALDH1A1 (0.61) | CYP1A2CYP2C19CYP2D6POLBLMNA | |
| SCHEMBL1610688 | 0.80 | TP53 (0.47) | CYP1A2CYP2C19CYP2D6POLBLMNA | |
| SCHEMBL1610914 | 0.80 | TP53 (0.47) | CYP1A2CYP2C19CYP2D6POLBLMNA | |
| SCHEMBL304116 | 0.79 | TDP1 (0.47) | LMNAMAPTMAPK1 | |
| SCHEMBL303521 | 0.79 | TDP1 (0.47) | LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354729-A | Controlling weeds at low dosage; nonphytotoxic | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0579469-A2 | N-acyldihydroquinoline derivatives as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-01-19 | — | — | EP | disclosed |