Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 17/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | AKR1A1 | P14550 | 5/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305849 | 0.90 | DYRK1A (0.43) | AKR1B1DYRK1AAKR1A1AKR1B10GLO1 | |
| SCHEMBL9305844 | 0.82 | DYRK1A (0.48) | AKR1B1DYRK1AAKR1A1AKR1B10GLO1 | |
| SCHEMBL8972535 | 0.81 | DYRK1A (0.45) | AKR1B1DYRK1AAKR1A1TRPV1 | |
| SCHEMBL8972967 | 0.81 | NPC1 (0.52) | TRPV1 | |
| SCHEMBL8973369 | 0.81 | HDAC6 (0.55) | AKR1B1ALOX5 | |
| SCHEMBL9443373 | 0.80 | NPC1 (0.41) | DYRK1ATRPV1 | |
| SCHEMBL9443106 | 0.79 | DYRK1A (0.49) | AKR1B1DYRK1AAKR1A1TRPV1ALOX5 | |
| SCHEMBL9304897 | 0.79 | NPC1 (0.54) | AKR1B1DYRK1A | |
| SCHEMBL9306671 | 0.79 | PPARA (0.46) | DYRK1A | |
| SCHEMBL9443212 | 0.79 | ALDH1A1 (0.43) | AKR1B1TRPV1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0375614-B1 | CORROSION-INHIBITING COATING COMPOSITIONS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | disclosed |
| US-5198482-A | Benzothiazole carboxylic acid amine salt | CIBA-GEIGY CORPORATION (US) | 1993-03-30 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0375614-A1 | Corrosion-inhibiting coating compositions | CIBA-GEIGY AG (CH) | 1990-06-27 | — | — | EP | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |