Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.70 |
| ▸ | HTR2B | P41595 | 1/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22439001 | 1.00 | LMNA (0.70) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL28527221 | 1.00 | LMNA (0.70) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL27320263 | 1.00 | LMNA (0.70) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL14438107 | 1.00 | LMNA (0.70) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL31406534 | 1.00 | LMNA (0.70) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL7954710 | 1.00 | LMNA (0.70) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL9309481 | 1.00 | LMNA (0.70) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL22324528 | 1.00 | LMNA (0.70) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL6770205 | 0.98 | MAPT (0.68) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL7956581 | 0.94 | MAPT (0.62) | LMNAMAPTMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |