SCHEMBL22324528

SCHEMBL22324528

CCCCCCCCOc1ccccc1C(=O)OC

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.70
MAPT P10636 3/20 0.70
MEN1 O00255 3/20 0.70
KMT2A Q03164 3/20 0.70
CYP3A4 P08684 2/20 0.70
NR1I2 O75469 1/20 0.70
CHRM2 P08172 1/20 0.70
ADRA2A P08913 1/20 0.70
OPRK1 P41145 1/20 0.70
HTR2B P41595 1/20 0.70
SLC6A3 Q01959 1/20 0.70
HDAC6 Q9UBN7 1/20 0.70
ALDH1A1 P00352 5/20 0.59
TSHR P16473 2/20 0.59
NPSR1 Q6W5P4 2/20 0.59
HSP90AA1 P07900 2/20 0.59
HTT P42858 1/20 0.59
PTPN11 Q06124 1/20 0.58
TP53 P04637 1/20 0.57
MAPK1 P28482 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22439001 1.00 LMNA (0.70) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL28527221 1.00 LMNA (0.70) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL27320263 1.00 LMNA (0.70) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL14438107 1.00 LMNA (0.70) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL9305910 1.00 LMNA (0.70) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL31406534 1.00 LMNA (0.70) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL7954710 1.00 LMNA (0.70) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL9309481 1.00 LMNA (0.70) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL6770205 0.98 MAPT (0.68) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL7956581 0.94 MAPT (0.62) LMNAMAPTMEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101693763-B Hydrogen-bond self-assembly super-molecular blue-fluorescence polymer and synthesis method thereof UNIV SICHUAN 2011-06-01 CN claimed
CN-101693763-A Hydrogen-bond self-assembly super-molecular blue-fluorescence polymer and symmetric method thereof UNIV SICHUAN 2010-04-14 CN claimed
CN-1274783-C Hexahydrogen bonded self-assembled supermolecular yellow-green luminescent material and its synthesizing method UNIV SICHUAN (CN) 2006-09-13 CN claimed
CN-1640983-A Hexahydrogen bonded self-assembled supermolecular yellow-green luminescent material and its synthesizing method UNIV SICHUAN (CN) 2005-07-20 CN claimed
US-11952330-B2 Antibiotic ammonium compounds and methods for the treatment of bacterial infections BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-04-09 US disclosed
US-20220098148-A1 ANTIBIOTIC AMMONIUM COMPOUNDS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-03-31 US disclosed
WO-2020163479-A1 ANTIBIOTIC AMMONIUM COMPOUNDS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2020-08-13 WO disclosed
CN-101693763-B Hydrogen-bond self-assembly super-molecular blue-fluorescence polymer and synthesis method thereof UNIV SICHUAN 2011-06-01 CN disclosed
CN-101693763-A Hydrogen-bond self-assembly super-molecular blue-fluorescence polymer and symmetric method thereof UNIV SICHUAN 2010-04-14 CN disclosed
CN-1274783-C Hexahydrogen bonded self-assembled supermolecular yellow-green luminescent material and its synthesizing method UNIV SICHUAN (CN) 2006-09-13 CN disclosed
CN-1640983-A Hexahydrogen bonded self-assembled supermolecular yellow-green luminescent material and its synthesizing method UNIV SICHUAN (CN) 2005-07-20 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220098148-A1 ANTIBIOTIC AMMONIUM COMPOUNDS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS ARG1, SLC10A2, ALPI LMNA 4324/4885MAPT 3702/4885MEN1 2565/4885
US-11952330-B2 Antibiotic ammonium compounds and methods for the treatment of bacterial infections ARG1, SLC10A2, ALPI LMNA 4324/4885MAPT 3702/4885MEN1 2565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.